Lean Body, Healthy Brain: The Wonders of C3G

Author: Chris Shugart

In the realm of health and wellness, substances that contribute to both a lean physique and a healthy brain are highly sought after. As a seasoned fitness enthusiast, my journey with supplements has evolved. In my youth, my focus was primarily on supplements for muscle gain or fat loss. However, as I've matured, while still aiming for body composition improvements, I've also embraced the concept of healthspan. Healthspan, a long - awaited concept from biomedicine, encompasses more than just longevity; it's about living an extended life free from disease and disability.

For years, I've been incorporating a body - composition supplement, C3G (cyanidin 3 - glucoside), into my routine. You can purchase it on Amazon. C3G exhibits remarkable properties. It effectively shrinks fat cells and restricts fat storage, all while promoting the growth and functionality of calorie - burning brown adipose tissue. Functioning as a natural glucose - disposal agent, it enables me to consume more carbohydrates, channeling them towards muscle development rather than storing them as body fat.

Recent research has unveiled another significant benefit of C3G, which aligns with my broader health goals: safeguarding against cognitive decline associated with aging.

C3G and Its Impact on the Brain

As the years pass, our brains undergo various changes. One of the concerning developments is the accumulation of amyloid - beta (Aβ) peptides. These peptides are fragments of a larger protein, amyloid precursor protein (APP), which is involved in normal brain function. In healthy brains, there is an efficient clearance mechanism for Aβ. However, over time, the balance between clearance and production can be disrupted. This disruption leads to the formation of plaques, oxidative damage to neurons, hyperphosphorylation of the protein tau, and ultimately, the development of neurofibrillary tangles, all hallmarks of Alzheimer's disease.

A study published in the Journal of Neuroinflammation demonstrated that oral administration of C3G over a 16 - week period led to a reduction in Aβ peptides. Additionally, C3G enhanced autophagy - related markers and improved synaptic plasticity, resulting in enhanced cognitive function. Although this study was conducted on mice with Alzheimer's, the findings are highly encouraging.

Another review in the European Journal of Pharmacology emphasized the neuroprotective effects of C3G in central nervous system disorders. C3G was shown to have preventive and therapeutic activities in conditions such as cerebral ischemia, Alzheimer's, Parkinson's, and multiple sclerosis. It achieved this by inhibiting oxidative stress and neuroinflammation and modulating the signaling pathways related to neuronal survival and function.

Furthermore, a related study published in Foods revealed that adults who consumed sticky black rice, a natural source of C3G, for five days experienced improvements in anxiety, depression, and stress perception.

Collectively, these studies suggest that C3G plays a natural and crucial role in supporting brain health and mitigating cognitive decline associated with neurodegenerative diseases.

Obtaining C3G

Black rice, blackberries, and blueberries contain trace amounts of C3G. However, to obtain a therapeutically effective dose, one would need to consume substantial quantities daily. As a more practical alternative, Indigo - 3G Nutrient Partitioning Agent, available on Amazon, contains 300 mg of C3G per serving. It is formulated with a specialized delivery system to enhance bioavailability.